Product Description
What is MOTS-c?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded within the mitochondrial genome. In research settings, it is widely explored for its role as a "mitochondrial signal" that regulates metabolic homeostasis. It is frequently studied for its involvement in the AMPK pathway, insulin sensitivity, cellular energy metabolism, and its potential effects as an exercise mimetic.
Key Research Highlights
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Metabolic Regulation: Investigated for its ability to regulate glucose metabolism and fatty acid oxidation.
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AMPK Pathway: Explored for its role in activating AMP-activated protein kinase (AMPK), a central regulator of cellular energy.
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Obesity & Insulin Studies: Studied in models of diet-induced obesity and insulin resistance.
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Muscle & Performance: Researched for its potential impact on physical performance and skeletal muscle adaptations.
Why Labs Choose This Material
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High-purity research grade with batch-linked documentation.
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Consistent lot-to-lot performance for reproducibility in metabolic assays.
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Secure, light-protective packaging to ensure peptide stability.
Specifications
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Synonyms: MOTS-c, Mitochondrial-Derived Peptide
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Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
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Form: Lyophilized powder (white)
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Purity: ≥98% (HPLC)
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Solubility: Soluble in water or PBS; reconstitute using sterile technique
Compliance & Notice
For laboratory research only.
FAQ
Is this for human consumption/weight loss? No—this listing is for research use only. It is not intended for use as a dietary supplement or therapeutic agent.
Do you provide a COA? Yes—a lot-specific Certificate of Analysis (COA) is included or available upon request.
What vial sizes are available? See size options on this page or request custom fills for specific experimental needs.